Ossifying fibromyxoid tumor of the oral cavity: rare case report and long-term follow-up

Authors

  • Maria Eduarda Pérez-de-Oliveira Universidade Estadual de Campinas, Faculdade de Odontologia de Piracicaba, Departamento de Diagnóstico Oral, Área de Semiologia e Patologia Oral
  • Thayná Melo de Lima Morais Universidade Estadual de Campinas, Faculdade de Odontologia de Piracicaba, Departamento de Diagnóstico Oral, Área de Semiologia e Patologia Oral
  • Márcio Ajudarte Lopes Universidade Estadual de Campinas, Faculdade de Odontologia de Piracicaba, Departamento de Diagnóstico Oral, Área de Semiologia e Patologia Oral
  • Oslei Paes de Almeida Universidade Estadual de Campinas, Faculdade de Odontologia de Piracicaba, Departamento de Diagnóstico Oral, Área de Semiologia e Patologia Oral
  • Willie F. P. van Heerden University of Pretoria, School of Dentistry, Department of Oral Pathology and Oral Biology
  • Pablo Agustin Vargas Universidade Estadual de Campinas, Faculdade de Odontologia de Piracicaba, Departamento de Diagnóstico Oral, Área de Semiologia e Patologia Oral,

DOI:

https://doi.org/10.4322/acr.2020.216

Keywords:

head and neck neoplasms, soft tissue neoplasms, mouth

Abstract

Ossifying fibromyxoid tumor (OFMT) is a rare mesenchymal soft tissue benign neoplasm with an uncertain line of differentiation, which arises most frequently in extremities. The head and neck region involvement is uncommon, with only ten intraoral cases published in the English-language literature. One additional case of OFMT is reported here, including a literature review of intraoral reported cases. A 45-year-old female patient presented a painless nodule involving the buccal mucosa of approximately two years duration, measuring nearly 1.3 cm in maximum diameter. The main histopathological features include ovoid to round cells embedded in a fibromyxoid matrix with a perpheral shell of lamellar bone. Immunohistochemically, the tumor showed immunoreactivity for vimentin and S100. No recurrence has been detected after 7 years of follow-up.

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Published

2021-01-04

Issue

Vol. 11 (2021)

Section

Clinical Case Report and Review

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How to Cite

Pérez-de-Oliveira, M. E. ., Morais, T. M. de L. ., Lopes, M. A. ., Almeida, O. P. de ., van Heerden, W. F. P. ., & Vargas, P. A. . (2021). Ossifying fibromyxoid tumor of the oral cavity: rare case report and long-term follow-up. Autopsy and Case Reports, 11, e2020216. https://doi.org/10.4322/acr.2020.216