Alcoholic foamy degeneration: an unusual presentation of the alcoholic liver disease diagnosed on autopsy

Authors

DOI:

https://doi.org/10.4322/acr.2023.446

Keywords:

Liver Diseases, Alcoholic, Pancreatitis, Acute Necrotizing, Autopsy

Abstract

Alcoholic foamy degeneration (AFD) is an uncommon presentation of alcoholic liver disease (ALD) with characteristic histologic findings of foamy-looking hepatocytes due to the presence of abundant microvesicles of fat within the cytoplasm predominantly in perivenular and midzonal regions without inflammation and fibrosis. It is underdiagnosed as the patients quickly recover after alcoholic abstinence and are rarely caught on biopsies. AFD has better prognosis than alcoholic hepatitis, and the injury mechanism is different, warranting a different diagnosis. We present an uncommon case of AFD incidentally diagnosed during autopsy in a chronic alcoholic and diabetic man.

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References

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Published

2023-10-11

Issue

Vol. 13 (2023)

Section

Autopsy Case Report

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Copyright (c) 2023 Autopsy and Case Reports

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How to Cite

Joshi, R., Parkhi, M. ., Gupta, A. ., Susngi, T. ., Kumar, A. ., Dhibar, D. P., & Mitra, S. . (2023). Alcoholic foamy degeneration: an unusual presentation of the alcoholic liver disease diagnosed on autopsy. Autopsy and Case Reports, 13, e2023446. https://doi.org/10.4322/acr.2023.446