Rare association between giant-cell aortitis and giant-cell aortic valvulitis
DOI:
https://doi.org/10.4322/acr.2023.449Keywords:
Aorta, Thoracic, Aortic Diseases, Aortic Aneurysm, Aortic Valve, Aortic Valve InsufficiencyAbstract
Giant cell arteritis (GCA) is a type of chronic vasculitis that affects medium and large-caliber arteries, frequently related to aortic involvement and, consequently, to aneurysm formation. However, associated valvulitis with giant cells is uncommon. We describe the case of a 50-year-old female patient with aortic aneurysm and valvular insufficiency, whose anatomopathological examination revealed giant-cell aortic valvulitis associated with giant cell aortitis.
Downloads
References
Ciofalo A, Gulotta G, Iannella G, et al. Giant cell arteritis: pathogenesis, clinical aspects and treatment approaches. Curr Rheumatol Rev. 2019;15(4):259-68. http://dx.doi.org/10.2174/1573397115666190227194014. PMid:30827250.
Sehra ST, Setty A. Giant cell arteritis - a series of cases and review of literature. Curr Rheumatol Rev. 2013;9(2):138-43. http://dx.doi.org/10.2174/1573397111309020009. PMid:25409672.
Souza AWS, Okamoto KYK, Abrantes F, Schau B, Bacchiega ABS, Shinjo SK. Giant cell arteritis: a multicenter observational study in Brazil. Clinics. 2013;68(3):317-22. http://dx.doi.org/10.6061/clinics/2013(03)OA06. PMid:23644850.
García-Martínez A, Arguis P, Prieto-González S, et al. Prospective long term follow-up of a cohort of patients with giant cell arteritis screened for aortic structural damage (aneurysm or dilation). Ann Rheum Dis. 2014;73(10):1826-32. http://dx.doi.org/10.1136/annrheumdis-2013-203322. PMid:23873881.
Evans JM, Bowles CA, Bjornsson J, Mullany CJ, Hunder GG. Thoracic aortic aneurysm and rupture in giant cell arteritis. A descriptive study of 41 cases. Arthritis Rheum. 1994;37(10):1539-47. http://dx.doi.org/10.1002/art.1780371020. PMid:7864947.
Spence RK, Estella F, Gisser S, Schiffman R, Camishion RC. Thoracic aortic aneurysm secondary to giant cell arteritis: a reappraisal of etiology, treatment and possible prevention. J Cardiovasc Surg. 1985;26(5):492-5. PMid:4030882.
Gelsomino S, Romagnoli S, Gori F, et al. Annuloaortic ectasia and giant cell arteritis. Ann Thorac Surg. 2005;80(1):101-5. http://dx.doi.org/10.1016/j.athoracsur.2005.01.063. PMid:15975349.
Svensson LG, Arafat A, Roselli EE, et al. Inflammatory disease of the aorta: patterns and classification of giant cell aortitis, Takayasu arteritis, and nonsyndromic aortitis. J Thorac Cardiovasc Surg. 2015;149(2, Suppl):S170-5. http://dx.doi.org/10.1016/j.jtcvs.2014.08.003. PMid:25218529.
Niclauss L, Letovanec I, Chassot PG, Gersbach PA, von Segesser LK. Acute aortic valve insufficiency and cardiogenic shock due to an isolated giant cell inflammation of the aortic valve leaflets: case report and review of the literature. J Heart Valve Dis. 2008;17(3):343-7. PMid:18592933.
Terré A, Lidove O, Georges O, Mesnildrey P, Chennebault H, Ziza JM. Non-infective endocarditis: expanding the phenotype of giant cell arteritis. Joint Bone Spine. 2019;86(1):115-6. http://dx.doi.org/10.1016/j.jbspin.2018.04.002. PMid:29709695.
Stone JR, Bruneval P, Angelini A, et al. Consensus statement on surgical pathology of the aorta from the Society for Cardiovascular Pathology and the Association for European Cardiovascular Pathology: I. Inflammatory diseases. Cardiovasc Pathol. 2015;24(5):267-78. http://dx.doi.org/10.1016/j.carpath.2015.05.001. PMid:26051917.
Downloads
Published
Issue
Section
License
Copyright (c) 2023 Autopsy and Case Reports
This work is licensed under a Creative Commons Attribution 4.0 International License.
Copyright
Authors of articles published by Autopsy and Case Report retain the copyright of their work without restrictions, licensing it under the Creative Commons Attribution License - CC-BY, which allows articles to be re-used and re-distributed without restriction, as long as the original work is correctly cited.