Current status of whitening agents and enzymes in Dentistry

Authors

  • Maria Cibelle Pauli Department Translational Medicine, Federal University of São Paulo, São Paulo, SP, Brazil
  • Michel Yudi Shinkai Kanemaru Department of Food Science, School of Food Engineering, University of Campinas, Campinas, Brazil
  • Waldemir Francisco Vieira-Junior Department of Restorative Dentistry https://orcid.org/0000-0001-8226-3100
  • Débora Alves Nunes Leite Lima Department of Restorative Dentistry, Piracicaba Dental School, University of Campinas, Piracicaba, São Paulo, Brazil
  • Juliano Bicas Department of Food Science, School of Food Engineering, University of Campinas, Campinas, Brazil
  • Gislaine Ricci Leonardi Faculty of Pharmaceutical Sciences, University of Campinas, Campinas, Brazil

DOI:

https://doi.org/10.1590/s2175-979020201000X32e19501%20

Keywords:

Dental bleaching, Biotechnology, Oxidoreductase enzymes

Abstract

This study reviews the knowledge on the use of conventional dental whitening and the use of enzymes as a new approach in bleaching. A review of the literature was based on academic articles and on patents related to the use of enzymes in dental bleaching. Tooth whitening techniques used nowadays are well reported in the literature, and its mechanism of action consists of an oxidoreduction reaction with the release of free radicals. The great instability of radicals, when in contact with the tissues, promotes oxidation and reduction in the size of the pigment chains incorporated into them. These pigments are eventually broken down into smaller and smaller molecular chains and end up being diffused from the dental structure. In turn, the use of enzymes aimed at tooth whitening can be a less harmful alternative to the tooth because their specificity regarding the substrate makes them of great interest to perform specific reactions, reducing collateral effects. The use of proteolytic enzymes and oxidoreductases paired with the application of peroxides, can be a promising alternative for obtaining even better results in the dental bleaching process.

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Published

2022-11-23

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Section

Review

How to Cite

Current status of whitening agents and enzymes in Dentistry. (2022). Brazilian Journal of Pharmaceutical Sciences, 58. https://doi.org/10.1590/s2175-979020201000X32e19501