Acetate wheat starch improving blood glucose response and bilan lipid on obesity dyslipidemia mice

Autores

  • Chu Thi Thu Hien Faculty of Pharmacy, Buon Ma Thuot University, Vietnam http://orcid.org/0000-0001-8173-0096
  • Phu Thi Hoa Department of Biochemistry, University of Medicine & Pharmacy, Hue University, Vietnam
  • Nguyen Hai Thuy Department of Internal Medicine, University of Medicine & Pharmacy, Hue University, Vietnam
  • Tran Huu Dung Faculty of Pharmacy, University of Medicine & Pharmacy, Hue University, Vietnam https://orcid.org/0000-0002-3283-9025

DOI:

https://doi.org/10.1590/s2175-97902022e20890

Palavras-chave:

Acetate wheat starch, Glucose, Lipid, Cholesterol

Resumo

Resistant starch is particularly concerned with beneficial effects in regulating blood glucose concentration and lipid metabolism, reducing the risk of diabetes and cardiovascular diseases. This study aimed to validate the effects of wheat starch acetate containing 32.1% resistant starch on postprandial blood glucose response and lipid profile on obesity, dyslipidemia Swiss mice induced by a high-fat diet. The result showed that there was a restriction on postprandial hyperglycemia and remained stable for 2 hours after meal efficiently comparing with the control group fed natural wheat starch. Simultaneously, when maintaining the dose of 5g/kg once or twice a day for 8 weeks, wheat starch acetate to be able to reduce body weight and blood glucose, triglyceride, cholesterol levels compared to the control group (p<0.05).

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Referências

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Publicado

2023-02-02

Edição

Seção

Original Article

Como Citar

Acetate wheat starch improving blood glucose response and bilan lipid on obesity dyslipidemia mice. (2023). Brazilian Journal of Pharmaceutical Sciences, 58. https://doi.org/10.1590/s2175-97902022e20890