Algae Metabolites as an Alternative in Prevention and Treatment of Skin Problems Associated with Solar Radiation and Conventional Photo-protection

Autores

  • Stefanie Rincón-Valencia Grupo de Investigación en Compuestos Funcionales, Facultad de Ciencias Exactas y Naturales, Universidad de Antioquia, Medellín, Colombia
  • Juan Camilo Mejía-Giraldo Grupo de Investigación en Compuestos Funcionales, Facultad de Ciencias Exactas y Naturales, Universidad de Antioquia, Medellín, Colombia; Facultad de Ciencias Farmacéuticas y Alimentarias, Universidad de Antioquia, Medellín, Antioquia, Colombia
  • Miguel Ángel Puertas-Mejía Grupo de Investigación en Compuestos Funcionales, Facultad de Ciencias Exactas y Naturales, Universidad de Antioquia, Medellín, Colombia https://orcid.org/0000-0002-9962-669X

DOI:

https://doi.org/10.1590/s2175-97902022e201046

Palavras-chave:

Caroteniods, Mycosporin like Amino Acids, Photoprotection, Solar radiation

Resumo

The histological structure and biochemistry of the skin is affected by solar radiation having adverse effects ranging from sunburns, premature aging that includes wrinkles, spots, dryness, and loss of collagen to cancer development. The skin has defense mechanisms to prevent damage caused by radiation, but when radiation exposure is excessive these mechanisms are not strong enough to protect the skin. The use of sunscreen is the most common practice of photo- protection. The active ingredients of these cosmetic protective formulations are generally from synthetic origin and have presented several drawbacks at the level of photo-stability, systemic absorption and can generate contact and photo-contact dermatitis. This review illustrates skin solar radiation problems, common sunscreen ingredients limitation and mentions how algae can be an alternative according to studies that have evaluated the photo-protective potential of extracts and compounds isolated by different techniques.

Downloads

Os dados de download ainda não estão disponíveis.

Referências

Addor FAS. Beyond photoaging: Additional factors involved in the process of skin aging. Clin Cosmet Investig Dermatol. 2018;11:437-43.

Amatu A, Imberti R. Oxidative stress in applied basic research and clinical practice - Studies on experimental models. Eur J Histochem. 2012;56(2):ejh.2012.br9.

Ariede MB, Candido TM, Morocho JAL, Robles VMV, de Carvalho JCM, Baby AR. Cosmetic attributes of algae - A review. Algal Res. 2017;25(5):483-87.

Bajpai R, Prokop A, Zappi M. Algal biorefineries: Cultivation of cells and products. Springer Science & Business Media. 2014;1:1-324.

Berthon JY, Nachat-Kappes R, Bey M, Cadoret JP, Renimel I, Filaire E. Marine algae as attractive source to skin care. Free Rad Res. 2017;51(6):555-67.

Cardozo KHM, Guaratini T, Barros MP, Falcão VR, Tonon AP, Lopes NP, et al. Metabolites from algae with economical impact. Comp Biochem Physiol Part C: Toxicol Pharmacol. 2007;146(1-2):60-78.

Coba LF, Aguilera AF, López F. Use of micosporine type amino acids (porfira 334) in the prevention of oxidation of cosmetic and pharmaceutical products. Patent number ES 2 301 437 B1. 2008a;12.

Coba LF, Aguilera AF, López F. Use of a purified mixture of micosporine type amino acids (asterine 330 + palitine) in products for the prevention of cancerigene processes. Patent number ES2303412B1 2008b;12.

Conde FR, Churio MS, Previtali CM. The photoprotector mechanism of mycosporine-like amino acids. excited-state properties and photostability of porphyra-334 in aqueous solution. J Photochem Photobiol B. 2000;56(2-3):139-44.

Copia J, Gaete H, Zúñiga G, Hidalgo M, Cabrera E. Efecto de la radiación ultravioleta b en la producción de polifenoles en la microalga marina Chlorella sp Lat Am J Aquat Res. 2012;40(1):113-23.

de la Coba F, Aguilera J, Korbee N, de Gálvez MV, Herrera-Ceballos E, Álvarez-Gómez, et al. UVA and UVB photoprotective capabilities of topical formulations containing mycosporine-like amino acids (MAAs) through different biological effective protection factors (BEPFs). Mar Drugs. 2019;17(1):55.

Dragicevic N, Maibach HI. Percutaneous penetration enhancers chemical methods in penetration enhancement: Drug manipulation strategies and vehicle effects. Springer- Verlag Berlin Heidelberg. 2015. 341pp

Dupont EJ, Gomez J, Bilodeau D. Beyond UV radiation: A skin under challenge. Int J Cosmetic Sci. 2013;35(3):224-32.

Geng R, Ren Y, Rao R, Tan X, Zhou H, Yang X, et al. Titanium dioxide nanoparticles induced hela cell necrosis under UVA radiation through the ROS-mPTP pathway. Nanomaterials. 2020;10(10):2029.

Gilbert E, Pirot F, Bertholle V, Roussel L, Falson F, Padois K. Commonly used UV filter toxicity on biological functions: Review of last decade studies. Int J Cosmet Sci. 2013;35(3):208-19.

Mejía GJC, Atehortúa L, Puertas MMA. Foto-protección: mecanismos bioquímicos, punto de partida hacia mejores filtros solares. DermatologíaCMQ. 2014;12(4):272-81.

González ZL. Percutaneous absorption of uv filters contained in sunscreen cosmetic products Springer International Publishing 2014. 216 pp.

Graham HK, Eckersley A, Ozols M, Mellody KT, Sherratt MJ. Human skin: Composition, Structure and visualisation methods. Ed. Georges Limbert. Springer Nature. 2019;1-18.

Han A, Chien AL, Kang S. Photoaging. Dermatol Clinic. 2014;32(3):291-99.

Hartmann A, Holzinger A, Ganzera M, Karsten U. Prasiolin, a new uv-sunscreen compound in the terrestrial green macroalga Prasiola calophylla (Carmichael Ex Greville) Kützing (Trebouxiophyceae, Chlorophyta). Planta. 2016;243(1):161-69.

Hiller J, Klotz K, Meyer S, Uter W, Hof K, Greiner A, et al. Systemic availability of lipophilic organic uv filters through dermal sunscreen exposure. Environ Int. 2019;132(7):105068.

Jansen R, Osterwalder U, Wang SQ, Burnett M, Lim HW. Photoprotection: Part II. Sunscreen: development, efficacy, and controversies. J Am Acad Dermatol. 2013b;69(6):867.e1-14.

Jansen R, Wang SQ, Burnett M, Osterwalder U, Lim HW. Photoprotection: Part I. Photoprotection by naturally occurring, physical, and systemic agents. J Am Acad Dermatol . 2013a;69(6):853.e1-12.

Jesumani V, Du H, Aslam M, Pei P, Huang N. Potential use of seaweed bioactive compounds in skincare-A review. Mar Drugs . 2019;17(12):688.

Karsten Ulf. Defense Strategies of algae and cyanobacteria against solar ultraviolet radiation. Algal Chem Ecol. 2008;273-96.

Kim SK, Pangestuti R. Potential role of marine algae on female health, beauty, and longevity. Adv Food Nutr Res. 2011;64:41-55.

Kockler J, Oelgemöller M, Robertson S, Glass BD. Photostability of sunscreens. J Photochem Photobiol C Photochem Rev. 2012;13(1):91-110.

Kozina LS, Borzova IV, Arutiunov VA, Ryzhak GA. Role of oxidative stress in skin aging. Adv Gerontol. 2012;25(2):217-22.

Kumar S, Baweja P, Sahoo D. Diatoms: Yellow or Golden Brown Algae. In: Sahoo D., Seckbach J. 2015. (eds) The Algae World. Cellular Origin, Life in Extreme Habitats and Astrobiology, vol 26. Springer, Dordrecht.

Lalegerie F, Lajili S, Bedoux G, Taupin L, Stiger-Pouvreau V, Connan S. Photo-protective compounds in red macroalgae from brittany: Considerable diversity in mycosporine-like amino acids (MAAs). Mar Environ Res. 2019;147(4):37-48.

Le Lann K, Surget G, Couteau C, Coiffard L, Cérantola S, Gaillard F, et al. Sunscreen, antioxidant, and bactericide capacities of phlorotannins from the brown macroalga Halidrys siliquosa J Appl Phycol. 2016;28(6):3547-59.

Lawrence KP, Long PF, Young AR. Mycosporine-like amino acids for skin photoprotection. Curr Med Chem. 2017;25(40):5512-27.

Lena, GD, Casini I, Lucarini M, Lombardi-Boccia G. Carotenoid profiling of five microalgae species from large- scale production. Food Res Int. 2019;120:810-18.

Łęska B, Messyasz B, Schroeder G. Application of algae biomass and algae extracts in cosmetic formulations. Algae Biomass Characterist Appl. 2018;89-101.

Lim HW, Arellano-Mendoza MI, Stengel F. Current challenges in photoprotection. J Am Acad Dermatol . 2017;76(3S1):S91-99.

López-Figueroa F, Aguilera J, Coba FL, Korbee N. Composición para protección solar a base de extractos de algas y líquenes. Patent ES2317741A1. 2009.

Lorigo M, Cairrao E. Antioxidants as stabilizers of UV filters: An example for the UV-B filter octylmethoxycinnamate. Biomed Dermatol. 2019;3(1):1-9.

Mancebo SE, Hu JY, Wang SQ. Sunscreens: a review of health benefits, regulations, and controversies. Dermatol Clin. 2014;32(3):427-38.

Maslin DL. Do suncreens protect us? Int J Dermatol. 2014;53(11):1319-23.

Mercurio DG, Wagemaker TAL, Alves VM, Benevenuto CG, Gaspar LR, Maia Campos PM. In Vivo photoprotective effects of cosmetic formulations containing uv filters, vitamins, ginkgo biloba and red algae extracts. J Photochem Photobiol B . 2015;153:121-26.

Mobin SMA, Chowdhury H, Alam F. Commercially important bioproducts from microalgae and their current applications-A review. Energy Procedia. 2019;160:752-60.

Morocho-Jácome AL, Freire TB, de Oliveira AC, de Almeida TS, Rosado C, Robles MVV, et al. In Vivo SPF from multifunctional sunscreen systems developed with natural compounds-A review. J Cosmet Dermatol. 2021;20(3):729-37.

Morocho-Jácome AL, Ruscinc N, Martinez RM, de Carvalho JCM, de Almeida TS, Rosado C, et al. (Bio) Technological aspects of microalgae pigments for cosmetics. Appl Microbiol Biotechnol. 2020;104(22):9513-22.

Nery ÉM, Martinez RM, Velasco MVR, Baby AR. A short review of alternative ingredients and technologies of inorganic UV filters. J Cosmet Dermatol . 2021;20(4):1061-65.

Norman RA, Menendez R. Structure and function of aging skin. In: Norman R.A. (eds) Diagnosis of Aging Skin Diseases. Springer, London. 2008;5-10.

Radulovich R, Umanzor S. Algas tropicales cultivo y uso como alimento. 1ra. ed. San José, C.R. Universidad de Costa Rica, Escuela de Ingeniería Agrícola, 2013; 52 p.

Rastogi RP, Sonan RRi, Madamwar D. UV photoprotectants from algae-synthesis and bio-functionalities. Algal Green Chemistry: Recent Progress in Biotechnology. Elsevier. 2017;17-38.

Ryu J, Park SJ, Kim IH, Choi YH, Nam TJ. Protective effect of porphyra-334 on uva-induced photoaging in human skin fibroblasts. Int J Mol Med. 2014;34(3):796-803.

Schmitz C, Ramlov F, de Lucena LAF, Uarrota V, Batista MB, Sissini MN. UVR and PAR absorbing compounds of marine brown macroalgae along a latitudinal gradient of the brazilian coast. J Photochem Photobiol B Biol. 2018;178(5):165-74.

Seebode C, Lehmann J, Emmert S. Photocarcinogenesis and skin cancer prevention strategies. Anticancer Res. 2016;36(3):1371-78.

Senevirathne WSM, Kim SK. Cosmeceuticals from algae. In: Functional ingredients from algae for food and nutraceuticals. (Ed) Herminia Dominguez Woodhead Publishing Limited. 2013;694-714.

Siller A, Blaszak SC, Lazar M, Harken EO. Update about the effects of the sunscreen ingredients oxybenzone and octinoxate on humans and the environment. Plast Surg Nurs. 2018;38(4):158-61.

Singer S, Karrer S, Berneburg M. Modern sun protection. Curr Opin Pharmacol. 2019;46:24-28.

Souza C, Campos PMBGM. Developmentandphotoprotective effect of a sunscreen containing the antioxidants spirulina and dimethylmethoxy chromanol on sun-induced skin damage. Eur J Pharm Sci. 2017;104(11):52-64.

Tobin DJ. Introduction to skin aging. J Tissue Viability. 2017;26(1):37-46.

Torres AE, Luk KM, Lim HW. Botanicals for photoprotection. Plast Aesthet Res. 2020;7:57.

Tosato MG, Orallo DE, Fangio MF, Diz V, Dicelio LE, Churio MS. Nanomaterials and natural products for UV- photoprotection. In: Grumezescu, A.M., Ed., Surface Chemistry of Nanobiomaterials, Elsevier, Amsterdam. 2016;359-392.

U.S. Food and Drug Administration. 2018. Enforcement Policy - OTC Sunscreen Drug Products Marketed Without an Approved Application. Center for Drug Evaluation and Research, Guideline for Industry.

Watson M, Holman DM, Maguire-Eisen M. Ultraviolet radiation exposure and its impact on skin cancer risk. Semin Oncol Nurs. 2016;32(3):241-54.

Wijesekara I, Kim SK, Li Y, Li YX. Phlorotannins as bioactive agents from brown algae. Process Biochem. 2011;46(12):2219-24.

Wijesinghe WAJP, Jeon YJ. Biological activities and potential industrial applications of fucose rich sulfated polysaccharides and fucoidans isolated from brown seaweeds: A review. Carbohydr Polym. 2012;88(1):13-20.

Wiznia LE, Elbuluk N. Differences in skin structure and function in ethnic populations. In: Vashi NA, Maibach HI, editors. Differences in skin structure and function in ethnic populations. New York: Springer International Publishing AG; 2017. p. 35-48

Wong T, Orton D. Sunscreen allergy and its investigation. Clin Dermatol. 2011;29(3):306-10.

Yeager DG, Lim HW. What’s new in photoprotection: A review of new concepts and controversies. Dermatol Clin . 2019;37(2):149-57.

Young AR, Claveau J, Rossi AB. Ultraviolet radiation and the skin: Photobiology and sunscreen photoprotection. J Am Acad Dermatol . 2017;76(3S1):S100-S109.

Downloads

Publicado

2023-02-15

Edição

Seção

Revisão

Como Citar

Algae Metabolites as an Alternative in Prevention and Treatment of Skin Problems Associated with Solar Radiation and Conventional Photo-protection. (2023). Brazilian Journal of Pharmaceutical Sciences, 58. https://doi.org/10.1590/s2175-97902022e201046

Dados de financiamento