Complicações cardiovasculares em pacientes hospitalizados Com COVID-19 e a repercussão sobre a mobilidade

Autores

DOI:

https://doi.org/10.1590/

Palavras-chave:

Covid-19, Sistema Cardiovascular, Limitação da Mobilidade, Serviço Hospitalar de Fisioterapia, Mobilização Precoce

Resumo

As manifestações cardiovasculares
ocasionadas pela covid-19 podem resultar em redução
da funcionalidade aguda, que persiste para além da
internação. Este estudo teve como objetivo descrever a
ocorrência de eventos cardiovasculares em pacientes
internados com covid-19 e identificar o impacto destes
sobre a mobilidade do paciente. Trata-se de um estudo
retrospectivo, realizado através da busca de dados em
prontuários digitais, no período compreendido entre
março de 2021 e março de 2022. Foram analisados 567
casos, dos quais 19,6% (n=111) dos pacientes apresentaram
eventos cardiovasculares na internação. A prevalência
foi no sexo masculino, com idade média de 47,5±9,8,
representando 52,3% (n=58) dos casos. A injúria do
miocárdio foi o evento cardiovascular mais frequente
e a arritmia cardíaca foi o principal evento associado
ao desfecho óbito (p=0,01). A ocorrência de eventos
cardiovasculares apresentou moderada correlação
negativa com a Escala de Mobilidade em Unidade de
Terapia Intensiva na alta hospitalar (p=0,05). A ocorrência
de eventos cardiovasculares em pacientes hospitalizados
por covid-19 foi de 19,6%, sendo que a ocorrência mais
frequente foi a injúria do miocárdio, estando esses eventos
associados à redução do nível de mobilidade.

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Referências

Zhao Y, Han X, Li C, Liu Y, Cheng J, et al. Covid-19 and the

cardiovascular system: a study of pathophysiology and

interpopulation variability. Front Microbiol. 2023;14:1213111.

doi: 10.3389/fmicb.2023.1213111

Davis MG, Bobba A, Majeed H, Bilal MI, Nasrullah A, et al.

Covid-19 With stress cardiomyopathy mortality and outcomes

among patients hospitalized in the united states: a propensity

matched analysis using the national inpatient sample

database. Curr Probl Cardiol. 2023;48(5):101607. doi: 10.1016/j.

cpcardiol.2023.101607

Keller K, Sagoschen I, Konstantinides S, Gori T, Münzel T, et al.

Incidence and risk factors of myocarditis in hospitalized patients

with covid-19. J Med Virol. 2023;95(3):e28646. doi: 10.1002/

jmv.28646

Hobohm L, Sagoschen I, Barco S, Farmakis IT, Fedeli U, et al.

Covid-19 infection and its impact on case fatality in patients

with pulmonary embolism. Eur Respir J. 2023;61(1):2200619.

doi: 10.1183/13993003.00619-2022

Schiavone M, Sozzi FB, Gasperetti A, Gobbi C, Gherbesi E,

et al. Clinical management of New-Onset Atrial Fibrillation

in covid-19 patients referred to a tertiary cardiac arrhythmia

center after hospital discharge. J Clin Med. 2022;11(19):5661.

doi: 10.3390/jcm11195661

Siddiqi HK, Weber B, Zhou G, Regan J, Fajnzylber J, Coxen K,

et al. Increased Prevalence of Myocardial Injury in Patients

with SARS-CoV-2 Viremia. Am J Med. 2021;134(4):542-6.

doi: 10.1016/j.amjmed.2020.09.046

Shi S, Qin M, Shen B, Cai Y, Liu T, et al. Association of cardiac

injury with mortality in hospitalized patients with covid-19 in

Wuhan, China. JAMA. Cardiol. 2020;5(7):802-10. doi: 10.1001/

jamacardio.2020.0950

Singh TK, Zidar DA, McCrae K, Highland KB, Englund K, et al.

A post-pandemic enigma: the cardiovascular impact of postacute

sequelae of SARS-CoV-2. Circ Res. 2023;132(10):1358-73.

doi: 10.1161/CIRCRESAHA.122.322228

Gyöngyösi M, Alcaide P, Asselbergs FW, Brundel BJJM, Camici

GG, et al. Long covid and the cardiovascular system-elucidating

causes and cellular mechanisms to develop targeted diagnostic

and therapeutic strategies: a joint Scientific Statement of

the ESC Working Groups on Cellular Biology of the Heart

and Myocardial and Pericardial Diseases. Cardiovasc Res.

;119(2):336-56. doi: 10.1093/cvr/cvac115

Núñez-Seisdedos MN, Lázaro-Navas I, López-González L,

López-Aguilera L. Intensive Care Unit- acquired weakness

and hospital functional mobility outcomes following invasive

mechanical ventilation in patients with covid-19: A singlecentre

prospective cohort study. J Intensive Care Med.

;37(8):1005-14. doi: 10.1177/08850666221100498

Ashton RE, Philips BE, Faghy M. The acute and chronic

implications of the covid-19 virus on the cardiovascular system

in adults: a systematic review. Prog Cardiovasc Dis. 2023;76:31-7.

doi: 10.1016/j.pcad.2023.01.003

Kawaguchi YM, Nawa RK, Figueiredo TB, Martins L, Pires-Neto

RC. Perme intensive care unit mobility score and ICU mobility

Scale: translation into Portuguese and cross-cultural adaptation

for use in Brazil. J Bras Pneumol. 2016;42(6):429-34. doi: 10.1590/

S1806-37562015000000301

Mouram S, Pannone L, Gauthey A, Sorgente A, Vergara P, et al.

Incidence and predictors of cardiac arrhythmias in patients with

covid-19. Front Cardiovasc Med. 2022;9:908177. doi: 10.3389/

fcvm.2022.908177

Brito D, Meester S, Yanamala N, Patel HB, Balcik BJ, et al.

High prevalence of pericardial involvement in college student

athletes recovering from covid-19. JACC Cardiovasc Imaging.

;14(3):541-55. doi: 10.1016/j.jcmg.2020.10.023

Pillarisetti J, Cheema MS, Haloot J, Panday M, Badin A, et al.

Cardiac complications of covid-19: incidence and outcomes.

Indian Heart J. 2022;74(3):170-7. doi: 10.1016/j.ihj.2022.04.008

Chen L, Hu W, Guo X, Zhao P, Tang J, et al. Association of

coagulation dysfunction with cardiac injury among hospitalized

patients with covid-19. Sci Rep. 2021;11(1):4432. doi: 10.1038/

s41598-021-83822-9

Guzik TJ, Mohiddin SA, Dimarco A, Patel V, Savvatis K, et al.

Covid-19 and the cardiovascular system: implications for risk

assessment, diagnosis, and treatment options. Cardiovasc Res.

;116(10):1666-87. doi: 10.1093/cvr/cvaa106

Sandor-Keri J, Benedek I, Polexa S, Benedek I. The Link

between SARS-CoV-2 infection, inflammation and

hypercoagulability-impact of hemorheologic alterations

on cardiovascular mortality. J Clin Med. 2021;10(14):3015.

doi: 10.3390/jcm10143015

Azevedo RB, Botelho BG, Hollanda JVG, Ferreira LVL, Junqueira

de Andrade LZ, et al. Covid-19 and the cardiovascular system:

a comprehensive review. J Hum Hypertens. 2021;35(1):4-11.

doi: 10.1038/s41371-020-0387-4

Saha SA, Russo AM, Chung MK, Deering TF, Lakkireddy D, et al.

Covid-19 and cardiac arrhythmias: a contemporary review. Curr

Treat Options Cardiovasc Med. 2022;24(6):87-107. doi: 10.1007/

s11936-022-00964-3

Malaty M, Kayes T, Amarasekera AT, Kodsi M, MacIntyre CR,

et al. Incidence and treatment of arrhythmias secondary to

coronavirus infection in humans: a systematic review. Eur J Clin

Invest. 2021;51(2):e13428. doi: 10.1111/eci.13428

Welmer AK, Angleman S, Rydwik E, Fratiglioni L, Qiu C.

Association of cardiovascular burden with mobility limitation

among elderly people: a population-based study. PLoS One.

;8(5):e65815. doi: 10.1371/journal.pone.0065815

Pleguezuelos E, Del Carmen A, Llorensi G, Carcole J,

Casarramona P, et al. Severe loss of mechanical efficiency

in covid-19 patients. J Cachexia Sarcopenia Muscle.

;12(4):1056-63. doi: 10.1002/jcsm.12739

Gentil P, Lira CAB, Vieira CA, Ramirez-Campillo R, Haghighi

AH, et al. Resistance training before, during, and after covid-19

infection: what have we learned so far? Int J Environ Res Public

Health. 2022;19(10):6323. doi: 10.3390/ijerph19106323

Andrade-Junior MC, Salles ICD, Brito CMM, Pastore-Junior L,

Righetti RF, et al. Skeletal muscle wasting and function

impairment in intensive care patients with severe

covid-19. Front Physiol. 2021;12:640973. doi: 10.3389/

fphys.2021.640973

Medrinal C, Prieur G, Bonnevie T, Gravier FE, Mayard D,

et al. Muscle weakness, functional capacities and recovery

for covid-19 ICU survivors. BMC Anesthesiol. 2021;21(1):64.

doi: 10.1186/s12871-021-01274-0

I TJ, Tsai YL, Cheng YY. Predictors of basic activity in daily living

and length of hospitalization in patients with covid-19. Healthcare

(Basel). 2022;10(8):1589. doi: 10.3390/healthcare10081589

Martínez-Velilla N, Casas-Herrero A, Zambom-Ferraresi F,

Sáez de Asteasu ML, Lucia A, et al. Effect of exercise intervention

on functional decline in very elderly patients during acute

hospitalization: a randomized clinical trial. JAMA Intern Med.

;179(1):28-36. doi: 10.1001/jamainternmed.2018.4869.

Erratum in: JAMA Intern Med. 2019;179(1):127

Prampart S, Le Gentil S, Bureau ML, Macchi C, Leroux C, et al.

Functional decline, long term symptoms and course of frailty at

-months follow-up in covid-19 older survivors, a prospective

observational cohort study. BMC Geriatr. 2022;22(1):542.

doi: 10.1186/s12877-022-03197-y

Wittmer VL, Paro FM, Duarte H, Capellini VK, Barbalho-Moulim

MC. Early mobilization and physical exercise in patients with

covid-19: a narrative literature review. Complement Ther Clin

Pract. 2021;43:101364. doi: 10.1016/j.ctcp.2021.101364

Publicado

2024-12-30

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Complicações cardiovasculares em pacientes hospitalizados Com COVID-19 e a repercussão sobre a mobilidade. (2024). Fisioterapia E Pesquisa, 31(cont), e23003824pt. https://doi.org/10.1590/