Mother's and newborn's plasmatic concentration of micronutrients at the moment of childbirth

Authors

  • Ciro João Bertoli Universidade de Taubaté; Departamento de Medicina
  • Claudio Leone Universidade de São Paulo; Faculdade de Saúde Pública; Departamento de Saúde Materno Infantil
  • Virginia B.V. Junqueira Universidade Federal de São Paulo; Escola Paulista de Medicina
  • Francisco Roque Carrazza Universidade de São Paulo; Faculdade de Medicina; Departamento de Pediatria

DOI:

https://doi.org/10.7322/jhgd.19965

Keywords:

retinol (vitamin A), &#946, -caroten, licopen, &#945, -tocopherol (vitamin E), cupper, newborns, pregnant women

Abstract

Cross sectional study of a sequential convenience sample of 73 non smokers' pregnant women with uncomplicated pregnancies and their normal newborns. The aim of the study was to compare plasmatic concentrations of retinol, β-carotene, licopen and α-tocopherol between mothers and their infants. Blood was obtained from parturient and umbilical cord for micronutrient analysis. HPLC was used for retinol, α-carotene, licopen and α-tocopherol analysis. Atomic absorption spectrophotometry was used for copper measurements. The sample was divided into 2 groups: group 1, with 38 women that had received vitamin and mineral supplementation during the last gestational trimester and group 2, with 35 women who have had no supplementation. Statistic comparison used Student t test or Wilcoxon test (alpha = 0.05). The groups of mothers were similar regarding age, parity, BMI and ingestion (low) of calories and micronutrients. The newborn groups had no differences according to sex, head circumference, weight and length. Plasmatic concentrations in group 1 of mothers were greater for retinol (p = 0.0034) and α-tocopherol (p = 0.0279). β-carotene, licopen and cupper showed no differences between the groups at mothers. In both newborn groups concentration of retinol, α-tocopherol and copper were quite similar and there was no clearly detectable licopen and ² carotene. In both, retinol, α-tocopherol and cupper showed larger concentration in mothers than in newborns (respectively p = 0.0003 and p = 0.0001). The conclusion is that newborn concentrations were systematically smaller than their mothers', independently of ingestion or supple-mentation during pregnancy.

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Published

2010-08-01

Issue

Vol. 20 No. 2 (2010)

Section

Original Research

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