Long-term chronic infection of a young immunocompromised patient by the SARS-CoV-2 P.2 VOI
DOI:
https://doi.org/10.1590/Keywords:
Sars-CoV-2, Persistence, Immunocompromised, Intra-host evolutionAbstract
An immunocompromised patient was infected by the SARS-CoV-2 variant of interest named Zeta (P.2) in February 2021. More than one year later, he suffered from symptomatic COVID-19 and sequencing revealed the same variant, which accumulated 23 substitutions. This case illustrates intra-host evolution of a particular SARS-CoV-2 variant, highlighting the importance of genomic surveillance of immunocompromised patients.
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Copyright (c) 2024 Camila Malta Romano, Vitor Gabriel Lopes da Silva, Luciane Sussuchi da Silva, Carolina Sanchez Aranda, Cristina Mendes de Oliveira, Marilda Mendonça Teixeira Siqueira, Elisa Cavalcante Pereira, Paola Cristina Resende, José Eduardo Levi, Maria Isabel de Moraes-Pinto

This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.
Funding data
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Conselho Nacional de Desenvolvimento Científico e Tecnológico
Grant numbers 313403/2018-0;311759/2022-0;313403/2018-0 313403/2018-0 -
Fundação de Amparo à Pesquisa do Estado de São Paulo
Grant numbers 2021/13419-6