Dengue in Brazil: epidemiological situation and contribution to a research agenda

Abstract

The epidemiological situation of dengue in Brazil is presented, showing the introduction and spread of vector and the different virus serotypes in Brazil. At the present time the Aedes aegypti, the vector, and 3 out of 4 existing virus serotypes (DENV-1, DENV-2 and DENV-3) are spread by virtually the entire national territory. The epidemiological picture has been characterized by recurrent epidemics, especially in large urban centers. A new characteristic in this scenario is the growth in the proportion of severe cases, particularly cases of dengue hemorrhagic fever. Existing control actions have been costly and ineffectives. In order to meet the gaps in existing knowledge, some elements for a research agenda are presented. Finally, we must recognize that problems such as dengue have their roots in the explosive form urban populations in countries such as Brazil has grown and in the conditions and lifestyles under which these people live.