Patients with Parkinson's disease under physiotherapeutic care present better pulmonary parameters than sedentary controls
DOI:
https://doi.org/10.1590/1809-2950/14415623012016Abstract
The aim of this study was to investigate the pulmonary parameters (spirometry and impulse oscillometry) of patients with Parkinson disease (PD) and healthy control peers, comparing the values of the subjects that were participating or not on a physiotherapeutic assistance program. Thirty-seven subjects were divided into four groups: two were formed by patients with PD (practitioners and non-practitioners of a physiotherapeutic protocol performed twice a week during 6 months) and the other two groups were formed by control peers (practitioners and non-practitioners of the same therapeutic protocol). The subjects underwent evaluation of chest cirtometry, spirometry and impulse oscillometry, being all the PD patients evaluated on the "off" state of their anti-PD medication. Data analysis occurred through the use of the non-parametric test of Kruskal-Wallis, with pairwise comparisons being done with Dunett T3 tests. Significance was set at 5%. Regarding the results, with a statistical similarity between groups for chest mobility, patients with PD who underwent the physiotherapeutic protocol showed better pulmonary parameters than sedentary patients. Comparison with control peers indicates better results of the PD group submitted to physiotherapy than sedentary controls. There were no differences in pulmonary parameters of both PD and control groups submitted to physiotherapy. In conclusion, the findings delimit promising results promoted by physiotherapy on pulmonary parameters in subjects with PD, and emphasize the need for more longitudinal studies of the clinical trial type for proof of cause and effect relationships.Downloads
References
Lalley PM. The aging respiratory system: pulmonary structure,
function and neural control. Respir Physiol Neurobiol.
;187(3):199-210.
Sanches SS, Santos FM, Fernandes JM, Santos MLM, Müller
PT, Christofoletti G. Neurodegenerative disorders increase
decline in respiratory muscle strength in older adults. Respir
Care. 2014;59(12):1838-45.
Sathyaprabha TN, Kapavarapu PK,.Pal PK, Thennarasu K,
Raju TR. Pulmonary Functions in Parkinson’s Disease. Indian
J Chest Dis Allied Sci. 2005; 47(4):251-7.
Pal PK, Shathyaprabha TN, Tuhina P, Thennarasu K. Pattern
of subclinical pulmonary dysfunction in Parkinson’s disease
and the effect of levodopa. Mov Disord. 2007;22(3):420-4.
Silverman EP, Sapienza CM, Saleem A, Carmichael C,
Davenport PW, Hoffma-Ruddy B et al. Tutorial on maximum
inspiratory and expiratory mouth pressures in individuals
with idiopathic Parkinson disease (IPD) and the preliminary
results of an expiratory muscle strength training program.
NeuroRehabilitation. 2006;21(1):71-9.
Huber JE, Darling M, Francis EJ, Zhang D. Impact of typical
aging and Parkinson’s disease on the relationship among
breath pausing, syntax, and punctuation. Am J Speech Lang
Pathol. 2012;21(4):368-79.
Monteiro L, Souza-Machado, Pinho P, Sampaio M, Nóbrega
AC, Melo A. Swallowing impairment and pulmonary
dysfunction in Parkinson’s disease: the silent threats. J Neurol
Sci. 2014;339(1-2):149-52.
Polatli M, Akyol A, Coldag O, Bayülkem K. Pulmonary function
tests in Parkinson’s disease. Eur J Neurol. 2001;8(4):341-5.
Reyes A, Ziman M, Nosaka K. Respiratory muscle training
for respiratory deficits in neurodegenerative disorders: a
systematic review. Chest. 2013;143(5):1386-94.
Hughes AJ, Daniel SE, Kilford L, Lees AJ. Accuracy of
clinical diagnosis of idiopathic Parkinson’s disease: a
clinico-pathological study of 100 cases. J Neurol Neurosurg
Psychiatry. 1992;55(3):181-4.
Hoehn MM, Yahr MD. Parkinsonism: onset, progression and
mortality. Neurology. 1967;17(5):427-42.
von Elm E, Altman DG, Egger M, Pocock SJ, Gøtzsche
PC, Vandenbroucke JP. The Strengthening the Reporting
of Observational Studies in Epidemiology (STROBE)
statement: guidelines for reporting observational studies. J
Clin Epidemiol. 2008;61(4):344-9.
Moher D. Consolidated Standards of Reporting Trials. JAMA.
;279(18):1489-91.
Folstein MF, Folstein SE, McHugh PR. Mini-Mental State: a
practical method for grading the cognitive state of patients
for clinician. J Psychiatr Res. 1975;12(3):189-98.
Brucki SMD, Nitrini R, Caramelli P, Bertolucci PHF, Okamoto
IH. Suggestions for utilization of the mini-mental state
examination in Brazil. Arq Neuropsiquiatr. 2003;61(3B):777-81.
Wilson RC, Jones PW. A comparison of the visual analogue
scale and modified Borg scale for the measurement of
dyspnea during exercise. Clin Sci. 1989;76(3):277-82.
American Thoracic Society statement: guidelines for the sixminute walk test. Am J Respir Crit Care Med. 2002;166(1):111-7.
Pereira CAC, Sato T, Rodrigues SC. Novos valores de
referência para espirometria forçada em brasileiros adultos
de raça branca. J Bras Pneumol. 2007;33(4):397-406.
Li CH, Chen WC, Liao WC, Tu CY, Lin CL, Sung FC et al.. The
association between chronic obstructive pulmonary disease
and Parkinson’s disease: a nationwide population-based
retrospective cohort study. QJM. 2015;108(1):39-45
Seccombe LM, Giddings HL, Rogers PG, Corbett AJ,
Hayes MW, Peters MJ et al. Abnormal ventilatory control
in Parkinson’s disease--further evidence for non-motor
dysfunction. Respir Physiol Neurobiol. 2011;179(2-3):300-4.
Polatli M, Akyol A, Cildag O, Bayülkem K. Pulmonary function
tests in Parkinson’s disease. Eur J Neurol. 2001;8(4):341-5.
Schulz H, Flexeder C, Behr J, Heier M, Holle R, Huber
RM et al. Reference values of impulse oscillometric lung
function indices in adults of advanced age. PLoS One.
;8(5):e63366.
Assumpção MS, Gonçalves RM, Ferreira LG, Schivinski CIS.
Sistema de oscilometria de impulso em pediatria: revisão de
literatura. Medicina. 2014;47(2):131-42.
Lanza Fde C, de Camargo AA, Archija LR, Selman JP, Malaguti
C, Dal Corso S. Chest wall mobility is related to respiratory
muscle strength and lung volumes in healthy subjects. Respir
Care. 2013;58(12):2107-12.
Monteiro L, Souza-Machado A, Valderramas S, Melo A. The
effect of levodopa on pulmonary function in Parkinson’s
disease: a systematic review and meta-analysis. Clin Ther.
(5):1049-55.
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