Thrombotic obstruction of the central venous catheter in patients undergoing hematopoietic stem cell transplantation

Authors

  • Kátia Michelli Bertoldi Arone Universidade de Brasília; Faculdade de Ciências da Saúde
  • Cleyton Zanardo de Oliveira Universidade de Brasília; Faculdade de Ciências da Saúde
  • Lívia Maria Garbin Universidade de Brasília; Faculdade de Ciências da Saúde
  • Paula Elaine Diniz dos Reis Universidade de Brasília; Faculdade de Ciências da Saúde
  • Cristina Maria Galvão Universidade de São Paulo; Escola de Enfermagem de Ribeirão Preto
  • Renata Cristina de Campos Pereira Silveira Universidade de São Paulo; Escola de Enfermagem de Ribeirão Preto

DOI:

https://doi.org/10.1590/S0104-11692012000400022

Keywords:

Central Venous Catheterization, Hematopoietic Stem Cell Transplantation, Bone Marrow Transplantation, Thrombosis

Abstract

This is an integrative literature review with the aim of summarizing the prevention measures and treatment of thrombotic obstruction of long-term semi-implanted central venous catheters, in patients undergoing hematopoietic stem cell transplantation. The sample consisted of seven studies, being two randomized controlled clinical trials, three cohort studies and two case series. Regarding the prevention measures, one single study demonstrated effectiveness, which was a cohort study on the oral use of warfarin. In relation to the treatment measures, three studies evidenced effectiveness, one highlighted the efficacy of streptokinase or urokinase, one demonstrated the benefit of using low-molecular-weight heparin and the other treated the obstruction with heparin or urokinase. Catheter patency research shows a restricted evolution that does not follow the evolution of transplantations, mainly regarding nursing care.

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Published

2012-08-01

Issue

Section

Review Article

How to Cite

Thrombotic obstruction of the central venous catheter in patients undergoing hematopoietic stem cell transplantation. (2012). Revista Latino-Americana De Enfermagem, 20(4), 804-812. https://doi.org/10.1590/S0104-11692012000400022