Treatment of acquired perforant dermatoses with allopurinol

Authors

DOI:

https://doi.org/10.11606/issn.2176-7262.rmrp.2022.164003

Keywords:

Allopurinol, Chronic renal insufficiency, Prurigo

Abstract

Perforating dermatoses are papulonodular cutaneous pathologies characterized by transepithelial extrusion of components of the extracellular matrix of the dermis, by inflammation or degeneration. When secondary, the systemic diseases are called Acquired Perforating Diseases. Our letter aims to report a case of acquired perforating dermatoses secondary to chronic renal dialysis. The treatment with Allopurinol proved to be effective in this case. Allopurinol would act as an antioxidant, reducing the inflammatory reaction in tissues and consequent damage to the collagen fibers.

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Author Biographies

  • Naomi Carrara Matsuura, College of Medicine CERES , São José do Rio Preto, (SP) Brazil

    Academic doctor

  • Fernanda Pereira, College of Medicine CERES , São José do Rio Preto, (SP) Brazil

    Academic doctor

  • Lissa Nakazato, College of Medicine CERES , São José do Rio Preto, (SP) Brazil

    Academic doctor

  • Luana Rocco Pereira Copi, College of Medicine CERES, São José do Rio Preto, (SP) Brazil

    Doctor Dermatologist

References

Badziak D, Lenhardt C, Barros MF, Mandelli FL, Serafini SZ, Santamaria JR. Acquired perforating dermatosis associated with hepatic impairment in a liver transplanted patient. An Bras Dermatol. 2007;82(1):53-6.

Dantas A, Melo G. A case of acquired perforating dermatosis. Portuguese Megazine General Clinic. 2011; 27:378-80.

Cordova KB, Oberg TJ, Malik M, Robinson-Bostom L (2009) Dermatologic conditions seen in end-stage renal disease. Semin Dial 22: 45-55.

Fernandes KAP, Guedes JCR, Dacri AM, Lima LA, Lima RB, et al. (2016) Dermatose perfurante adquirida em paciente com insuficiência renal crônica -Relato de Caso. An Bras Dermatol 91: 10-13.

Gerhardt CMB, Gussão BC, Matos JPS, Lugon JR, Pinto JMN. Dermatological alterations in hemodialysis and transplanted patients. Brazilian Newspaper of Nephrology. 2011; 33(2):268-275

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Published

2022-11-09

Issue

Vol. 55 No. 3 (2022)

Section

Relato de Caso

License

Copyright (c) 2022 Naomi Carrara Matsuura, Fernanda Pereira, Lissa Nakazato, Luana Rocco Pereira Copi

Creative Commons License

This work is licensed under a Creative Commons Attribution 4.0 International License.

 

 

How to Cite

1.
Matsuura NC, Pereira F, Nakazato L, Copi LRP. Treatment of acquired perforant dermatoses with allopurinol. Medicina (Ribeirão Preto) [Internet]. 2022 Nov. 9 [cited 2025 Mar. 12];55(3):e-164003. Available from: https://periodicos.usp.br/rmrp/article/view/164003