Organochlorate residues in mammary adipose tissue and their relation with to breast cancer

Abstract

Taking into consideration the sanitary repercussion that organochlorate residues may have, levels of organochlorate pesticides and polychlorate biphenyls were determinated in samples of adipose tissue from donors with mammary cancer (group with malignant pathology) and beneficial alteration (group control). Furthermore, a study was made about these women epidemiologic data and, posteriorlly, the relation organochlorate residues/epidemiologic data was studed. The levels of Aldrin, PCB congener n° 28 and PCB n° 52 were statistically different in the control and malignant pathology groups. The mean concentrations of these compounds were lower in the control group than in the malignant pathology group, and this suggests the possibility of a positive relation between these residues and the malignancy of the tumours.