Relação entre marcadores hematológicos, endócrinos e imunológicos e a sarcopenia em idosos
DOI:
https://doi.org/10.11606/issn.2317-0190.v29i2a181686Palavras-chave:
Sarcopenia, Força Muscular, Velocidade de Marcha, Biomarcadores, IdosoResumo
Objetivo: Relacionar os marcadores hematológicos, endócrinos e imunológicos com os critérios de classificação da sarcopenia em idosos residentes na comunidade. Métodos: Estudo transversal, vinculado à pesquisa institucional “Atenção Integral à Saúde do Idoso”. A população foi composta por indivíduos com idade igual ou superior a 60 anos, ambos os sexos, usuários da atenção primária à saúde. O protocolo de pesquisa contemplou entrevista, avaliação da sarcopenia e exames laboratoriais para avaliação do hemograma, da 25-hidroxivitamina D, paratormônio, fator de crescimento semelhante à insulina-1, interleucina-6 e proteína C reativa. Para análise estatística utilizou-se Teste de Mann-Whitney, Teste de qui-quadrado de Pearson, Exato de Fisher e Odds Ratio. Resultados: Verificou-se relação de interleucina-6 (p= 0,004), eritrócitos (p= 0,038), hemoglobina (p<0,001) e hematócrito (p= 0,002) com sarcopenia. Também observou-se que os idosos com força muscular alterada apresentaram valores mais baixos de hematócrito (p= 0,037) e mais altos de interleucina-6 (p= 0,002); e com desempenho físico alterado apresentaram valores mais baixos de leucócitos (p=0,024), hemoglobina (p<0,001), hematócrito (p= 0,007) e 25-hidroxivitamina D (p= 0,034) e mais altos de paratormônio (p= 0,018) e interleucina-6 (p= 0,002). Conclusão: Sugere-se a avaliação e acompanhamento dos níveis de interleucina-6, paratormônio, 25-hidroxivitamina D e da série vermelha do hemograma durante a prática assistencial.
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