Neuroimaging and motor development of twins with congenital microcephaly associated with Zika virus: a case report
DOI:
https://doi.org/10.11606/issn.2317-0190.v28i3a181212Keywords:
Microcephaly, Motor Skills Disorders, Zika Virus, Neuroimaging, RehabilitationAbstract
Objective: We aimed to describe a case of congenital microcephaly caused by Zika virus infection in a monozygotic twin pregnancy. Methods: Transfontanelle ultrasonography and cranial computed tomography revealed different lesion patterns for both twins with congenital microcephaly caused by Zika virus infection. Motor development assessments were performed using the Alberta Infant Motor Scale and the Gross and Motor Function Measure before, during, and after physiotherapy. Results: The evaluations showed differences in motor acquisition between the twins. The values in the first case were much lower than those in the second case, which showed more motor delay. Conclussion: The present study showed that despite the twins being monozygotic, the effects of neurological lesions as revealed by neuroimaging were worse in the first case, and even with two weekly rehabilitation sessions, motor development over time was considerably worse in the twin in case 1 than in the other twin.
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