High-risk human papillomavirus infection and associated factors in the anal canal of HIV-positive patients in Medellín, 2017–2018

Autores

DOI:

https://doi.org/10.11606/s1518-8787.2020054001692

Palavras-chave:

Human Papillomavirus Infections, Epidemiology, HIV Infections, Anal Neoplasia, Sexual Behavior, Risk Factors, Socioeconomic Factors

Resumo

OBJECTIVE: To estimate the prevalence of high-risk human papillomavirus (HR-HPV) anal infection and associated factors in human immunodeficiency virus (HIV) positive patients in Medellín. METHODS: Descriptive cross-sectional study in 300 HIV-positive patients, adults, with history of anal intercourse, treated in two health care services of Medellín 2017–2018. We conducted a structured survey on sociodemographics, sexual behavior and medical history. HPV was detected in anal swabs tested by the COBAS 4800 system. Exploratory data analysis of risk factors associated with HR-HPV was conducted by chi-square test of independence and both raw and adjusted prevalence ratios used the Poisson regression model, at a 95% confidence interval. RESULTS: The high-risk HPV had a prevalence of 82.7%; HPV16 had a prevalence of 32.7%, HPV18 a prevalence of 21.7% and other HPV types scored 78.3%. The high-risk HPV prevalence in women was of 68.2% and 83.8% in men. The risk factors associated with high-risk HPV after adjustment were age under 30 years, elementary education, casual sex partners, and first sexual activity before 18 years old. CONCLUSIONS: The high incidence of high-risk HPV, along with the occurrence of coinfections by multiple types in the study population shows their susceptibility to develop some type of anal intra-epithelial neoplasia. It is important to establish sexual health programs focused on primary health care.

Biografia do Autor

  • Daniela Herrera Posada, Universidad de Antioquia

    Universidad de Antioquia. Escuela de Microbiología. Medellín, Antioquia, Colombia

  • Lucia Stella Tamayo Acevedo, Universidad de Antioquia

    Universidad de Antioquia. Escuela de Microbiología. Medellín, Antioquia, Colombia

  • Marleny Valencia Arredondo, Universidad de Antioquia

    Universidad de Antioquia. Escuela de Microbiología. Medellín, Antioquia, Colombia

  • Gloria Inéz Sánchez Vásquez, Universidad de Antioquia

    Universidad de Antioquia. Facultad de Medicina. Medellín, Antioquia, Colombia

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Publicado

2020-11-20

Edição

Seção

Artigos Originais

Como Citar

Posada, D. H., Acevedo, L. S. T., Arredondo, M. V., & Vásquez, G. I. S. (2020). High-risk human papillomavirus infection and associated factors in the anal canal of HIV-positive patients in Medellín, 2017–2018. Revista De Saúde Pública, 54, 93. https://doi.org/10.11606/s1518-8787.2020054001692