Seroprevalence of human parvovirus B19 in a suburban population in São Paulo, Brazil
DOI:
https://doi.org/10.1590/S0034-89102008005000019Keywords:
Parvoviridae Infections^i1^sepidemiol, Parvovirus B19, Human, Risk Groups, Seroepidemiologic StudiesAbstract
OBJECTIVE: To analyze the prevalence of IgG antibodies to human parvovirus B19. METHODS: Cross-sectional study in a suburban community in São Paulo, Southeastern Brazil, between November 1990 and January 1991. Randomly selected (N=435) representative samples of sera were collected from healthy children older than 15 days old and adults up to 40 years old. IgG antibodies were detected using ELISA. RESULTS: High prevalence of IgG antibodies to B19 parvovirus was found in 87% of newborns. The prevalence of maternally derived IgG antibodies exponentially plunged up to the 19th month of age. Low prevalence of antibodies was found in the first 4 years of life, increasing up to 72% in those aged 31-40 years. It was estimated that the average age of first infection in this population is 21 ± 7 years old and the optimal age for vaccination with a hypothetical vaccine would be 1 year of age. CONCLUSIONS: Parvovirus B19 IgG antibody prevalence was high in newborns and those aged 31-40 years. The analysis by age groups showed a pattern similar to that found in previous studies, i.e., low prevalence of infection in children that increases with age.Downloads
Published
2008-06-01
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Original Articles
How to Cite
Huatuco, E. M. M., Durigon, E. L., Lebrun, F. L. A. S., Passos, S. D., Gazeta, R. E., Azevedo Neto, R. S., & Massad, E. (2008). Seroprevalence of human parvovirus B19 in a suburban population in São Paulo, Brazil . Revista De Saúde Pública, 42(3), 443-449. https://doi.org/10.1590/S0034-89102008005000019