The response of the global scientific community in the fight against COVID-19
DOI:
https://doi.org/10.11606/issn.2317-2770.v26i2p81-87Keywords:
COVID-19, Ethics, Research, Epidemiologic Study CharacteristicsAbstract
The Covid-19 pandemic began at the end of 2019 and imposed significant challenges on the academic community. This research aimed to observe the landscape of clinical research involving Covid-19 and verify the scientific community’s engagement with the subject by comparing the number of projects on this specific illness to those on other more prevalent diseases. The official data released by ClinicalTrials.org were used. Covid-19 and the diseases considered major causes of death were researched in the named database using keywords between 01/01/2020 and 31/12/2021 and in the biennium before the pandemic (2018-2019), respectively. Data analysis showed the academic community’s commitment in all regions of the world, with a higher incidence of studies focused on Covid-19 than on other important diseases. Interventional and observational studies were quantitatively similar, both directed at adults and older adults of both sexes.
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World Health Organization. COVID-19 Weekly Epidemiological Update [Internet]. Geneva: WHO; 2020. [Acesso em 2021 out. 24]. Disponível em: https://www.who.int/publications/m/item/weekly-epidemiological-update---29-december-2020
Hsiang S, Allen D, Annan-Phan S, Bell K, Bolliger I, Chong T, et al. The effect of large-scale anti-contagion policies on the COVID-19 pandemic. Nature. 2020;584(7820):262–7. DOI: https://doi.org/10.1038/s41586-020-2404-8
Hatchett RJ, Mecher CE, Lipsitch M. Public health interventions and epidemic intensity during the 1918 influenza pandemic. PNAS. 2007;104(18):7582–7. DOI: https://doi.org/10.1073/pnas.0610941104
Liu X, Xu X, Li G, Xu X, Sun Y, Wang F, et al. Differential impact of non-pharmaceutical public health interventions on COVID-19 epidemics in the United States. BMC Public Health. 2021;21(1):965. DOI: https://doi.org/10.1186/s12889-021-10950-2
World Health Organization. WHO guidance on research methods for health emergency and disaster risk management [Internet]. Geneva: WHO; 2021. [Acesso em 2021 out. 24]. Disponível em: https://apps.who.int/iris/handle/10665/345591
Nalbandian A, Sehgal K, Gupta A, Madhavan MV, McGroder C, Stevens JS, et al. Post-acute COVID-19 syndrome. Nat Med. 2021;27(4):601–15. DOI: https://doi.org/10.1038/s41591-021-01283-z
World Health Organization. The top 10 causes of death [Internet]. Geneva; 2019 [Acesso em 2021 out. 24]. Disponível em: https://www.who.int/news-room/fact-sheets/detail/the-top-10-causes-of-death
Hossain MK, Hassanzadeganroudsari M, Feehan J, Apostolopoulos V. The race for a COVID-19 vaccine: where are we up to? Expert Rev Vaccines [Internet]. 2021 [Acesso em 2022 jan. 12];21(3):355-76. Disponível em: https://pubmed.ncbi.nlm.nih.gov/34937492/. DOI: https://doi.org/10.1080/14760584.2022.2021074
Castro-Silva II, Maciel JAC. Panorama de pesquisas com seres humanos sobre Covid-19 no Brasil. Rev bioét (Impr.). 2020;28(4):655-63. DOI: https://doi.org/10.1590/1983-80422020284429
Brasil. Ministério da Saúde. Conselho Nacional de Saúde. Resolução nº 466, de 12 de dezembro de 2012. Aprovação de diretrizes e normas regulamentadoras de pesquisas envolvendo seres humanos [Internet]. Diário Oficial [da] República Federativa do Brasil. 2012 dez. 12 [Acesso em 2021 out. 24]. Disponível em: https://bvsms.saude.gov.br/bvs/saudelegis/cns/2013/res0466_12_12_2012.html
Sontag S. Doença como metáfora / AIDS e suas metáforas. São Paulo: Companhia de Bolso; 2007.
Razzaghi H, Masalovich S, Srivastav A, Black CL, Nguyen KH, de Perio MA, et al. COVID-19 vaccination and intent among Healthcare Personnel, U.S. Am J Prev Med. In press 2021.
Savoia E, Su M, Piltch-Loeb R, Masterson E, Testa MA. COVID-19 vaccine early skepticism, misinformation and informational needs among essential workers in the USA. Int J Environ Res Public Health. 2021;18(24):13244. DOI: https://doi.org/10.3390/ijerph182413244
World Health Organization. Vaccination in acute humanitarian emergencies: a framework for decision making [Internet]. Geneva: WHO; 2017 [Acesso em 2021 out. 24]. Disponível em: https://apps.who.int/iris/handle/10665/255575
Greene SK, Levin-Rector A, McGibbon E, Baumgartner J, Devinney K, Ternier A, et al. Reduced COVID-19 hospitalizations among New York City residents following age-based SARS-CoV-2 vaccine eligibility: Evidence from a regression discontinuity design. Vaccine X [Internet]. 2021 [Acesso em 2022 jan 12];10:100134. Disponível em: https://pubmed.ncbi.nlm.nih.gov/34961848/. DOI: https://doi.org/10.1016/j.jvacx.2021.100134
Vilches TN, Sah P, Moghadas SM, Shoukat A, Fitzpatrick MC, Hotez PJ, et al. COVID-19 hospitalizations and deaths averted under an accelerated vaccination program in northeastern and southern regions of the USA. Lancet Reg Health Am [Internet]. 2021 [Acesso em 2022 jan. 12];6:100147. Disponível em: https://pubmed.ncbi.nlm.nih.gov/34977848/. DOI: https://doi.org/10.1016/j.lana.2021.100147
Brasil. Ministério da Saúde. Conselho Nacional de Saúde. Resolução no 510, de 7 de abril de 2016. Dispõe sobre as normas aplicáveis a pesquisas em Ciências Humanas e Sociais cujos procedimentos metodológicos envolvam a utilização de dados diretamente obtidos com os participantes ou de informações identificáveis ou que possam acarretar riscos maiores do que os existentes na vida cotidiana. Diário Oficial da União. 2016 mai. 24; Seção 1. p. 44-6.
Conti PHB, de Souza PVS. Bioética e seus paradigmas teóricos. Rev bioét (Impr.). 2021;29(4):716-26. DOI: https://doi.org/10.1590/1983-80422021294505
Begg C, Cho M, Eastwood S, Horton R, Moher D, Olkin I, et al. Improving the quality of reporting of randomized controlled trials: The CONSORT statement. JAMA. 1996;276(8):637-9. DOI: https://doi.org/10.1001/jama.276.8.637
Alexander PE, Debono VB, Mammen MJ, Iorio A, Aryal K, Deng D, et al. COVID-19 coronavirus research has overall low methodological quality thus far: case in point for chloroquine/hydroxychloroquine. J Clin Epidemiol [Internet]. 2020 [Acesso em 2021 out. 24];123:120–6. Disponível em: https://pubmed.ncbi.nlm.nih.gov/32330521/. DOI: https://doi.org/10.1016/j.jclinepi.2020.04.016
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Copyright (c) 2021 Janaina Paiva Curi, Dayane Batista Santana, Rodolfo Francisco Haltenhoff Melani, Thiago Leite Beaini
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