Patients with chronic migraine present persistent functional disorders in the interictal phase: observational case-control study

Authors

DOI:

https://doi.org/10.11606/issn.2317-0190.v31i3a224224

Keywords:

Migraine Disorders, Range of Motion, Articular, Pain, Neck Pain

Abstract

Objective: To investigate the presence of functional deficits in people with chronic migraine during the interictal phase, focusing on cervical range of movement, intensity of pain during movement, cervical disability and physical activity levels. Method: Observational case-control study carried out with patients with chronic migraine and healthy individuals between January 2019 and March 2020, aged between 18 and 55 years. Cervical range of movement (inclinometer), intensity of pain during movement (Numerical Pain Scale), cervical disability (Cervical Disability Index) and level of physical activity (International Physical Activity Questionnaire) were measured. Results: 32 patients with chronic migraine and 32 healthy controls were included. The group with chronic migraine had a lower range of motion in all cervical movements (p<0.05), except right cervical rotation (p= 0.054), as well as greater pain intensity during extension (p=0.012) and right rotation (p= 0.015). Cervical disability was significantly higher in the migraine group when compared to the control group (p<0.001). The level of physical activity was similar between the groups (p= 0.839). Conclusion: This study demonstrated that individuals with chronic migraine in the interictal phase present several functional deficits compared to healthy individuals. Specifically, we observed a significant reduction in cervical range of motion, a greater intensity of pain with cervical movement in some cases, and cervical disability ranging from mild to moderate. However, there was no significant difference in physical activity levels between the groups.

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References

Headache Classification Committee of the International Headache Society (IHS) The International Classification of Headache Disorders, 3rd edition. Cephalalgia. 2018;38(1):1-211. Doi: https://doi.org/10.1177/0333102417738202

Mier RW, Dhadwal S. Primary Headaches. Dent Clin North Am. 2018;62(4):611-628. Doi: https://doi.org/10.1016/j.cden.2018.06.006

Maleki N, Szabo E, Becerra L, Moulton E, Scrivani SJ, Burstein R, et al. Ictal and interictal brain activation in episodic migraine: Neural basis for extent of allodynia. PLoS One. 2021;16(1):e0244320. Doi: https://doi.org/10.1371/journal.pone.0244320

Ashina S, Bentivegna E, Martelletti P, Eikermann-Haerter K. Structural and Functional Brain Changes in Migraine. Pain Ther. 2021;10(1):211-223. Doi: https://doi.org/10.1007/s40122-021-00240-5

GBD 2016 Disease and Injury Incidence and Prevalence Collaborators. Global, regional, and national incidence, prevalence, and years lived with disability for 328 diseases and injuries for 195 countries, 1990-2016: a systematic analysis for the Global Burden of Disease Study 2016. Lancet. 2017;390(10100):1211-1259. Doi: https://doi.org/10.1016/S0140-6736(17)32154-2

Krøll LS, Hammarlund CS, Westergaard ML, Nielsen T, Sloth LB, Jensen RH, et al. Level of physical activity, well-being, stress and self-rated health in persons with migraine and co-existing tension-type headache and neck pain. J Headache Pain. 2017;18(1):46. Doi: https://doi.org/10.1186/s10194-017-0753-y

Carvalho GF, Chaves TC, Gonçalves MC, Florencio LL, Braz CA, Dach F, et al. Comparison between neck pain disability and cervical range of motion in patients with episodic and chronic migraine: a cross-sectional study. J Manipulative Physiol Ther. 2014;37(9):641-6. Doi: https://doi.org/10.1016/j.jmpt.2014.09.002

Ferracini GN, Florencio LL, Dach F, Bevilaqua Grossi D, Palacios-Ceña M, Ordás-Bandera C, et al. Musculoskeletal disorders of the upper cervical spine in women with episodic or chronic migraine. Eur J Phys Rehabil Med. 2017;53(3):342-350. Doi: https://doi.org/10.23736/S1973-9087.17.04393-3

Luedtke K, Starke W, May A. Musculoskeletal dysfunction in migraine patients. Cephalalgia. 2018;38(5):865-875. Doi: https://doi.org/10.1177/0333102417716934

Amin FM, Aristeidou S, Baraldi C, Czapinska-Ciepiela EK, Ariadni DD, Di Lenola D, et al. The association between migraine and physical exercise. J Headache Pain. 2018;19(1):83. Doi: https://doi.org/10.1186/s10194-018-0902-y

Malta M, Cardoso LO, Bastos FI, Magnanini MMF, Silva CMFP. Iniciativa STROBE: subsídios para a comunicação de estudos observacionais. Rev Saúde Pública. 2010;44(3):559–65. Doi: https://doi.org/10.1590/S0034-89102010000300021

Pourahmadi MR, Bagheri R, Taghipour M, Takamjani IE, Sarrafzadeh J, Mohseni-Bandpei MA. A new iPhone application for measuring active craniocervical range of motion in patients with non-specific neck pain: a reliability and validity study. Spine J. 2018;18(3):447-457. Doi: https://doi.org/10.1016/j.spinee.2017.08.229

Florêncio LL, Pereira PA, Silva ER, Pegoretti KS, Gonçalves MC, Bevilaqua-Grossi D. Agreement and reliability of two non-invasive methods for assessing cervical range of motion among young adults. Rev Bras Fisioter. 2010;14(2):175-81.

Chiarotto A, Maxwell LJ, Ostelo RW, Boers M, Tugwell P, Terwee CB. Measurement Properties of Visual Analogue Scale, Numeric Rating Scale, and Pain Severity Subscale of the Brief Pain Inventory in Patients With Low Back Pain: A Systematic Review. J Pain. 2019;20(3):245-263. Doi: https://doi.org/10.1016/j.jpain.2018.07.009

Ferreira-Valente MA, Pais-Ribeiro JL, Jensen MP. Validity of four pain intensity rating scales. Pain. 2011;152(10):2399-2404. Doi: https://doi.org/10.1016/j.pain.2011.07.005

Farrar JT, Young JP Jr, LaMoreaux L, Werth JL, Poole MR. Clinical importance of changes in chronic pain intensity measured on an 11-point numerical pain rating scale. Pain. 2001;94(2):149-158. Doi: https://doi.org/10.1016/S0304-3959(01)00349-9

Cook C, Richardson JK, Braga L, Menezes A, Soler X, Kume P, et al. Cross-cultural adaptation and validation of the Brazilian Portuguese version of the Neck Disability Index and Neck Pain and Disability Scale. Spine (Phila Pa 1976). 2006;31(14):1621-7. Doi: https://doi.org/10.1097/01.brs.0000221989.53069.16

Pietrobon R, Coeytaux RR, Carey TS, Richardson WJ, DeVellis RF. Standard scales for measurement of functional outcome for cervical pain or dysfunction: a systematic review. Spine (Phila Pa 1976). 2002;27(5):515-22. Doi: https://doi.org/10.1097/00007632-200203010-00012

Matsudo S, Araújo T, Matsudo V, Andrade D, Andrade E, Oliveira LC, et al. Questionário Internacional de Atividade Física (IPAQ): Estudo de Validade e Reprodutibilidade no Brasil. Rev Bras Ativ Fís Saúde. 2001;6(2):05-18.

Aguila MR, Rebbeck T, Pope A, Ng K, Leaver AM. Six-month clinical course and factors associated with non-improvement in migraine and non-migraine headaches. Cephalalgia. 2018;38(10):1672-1686. Doi: https://doi.org/10.1177/0333102417744360

Krøll LS, Hammarlund CS, Linde M, Gard G, Jensen RH. The effects of aerobic exercise for persons with migraine and co-existing tension-type headache and neck pain. A randomized, controlled, clinical trial. Cephalalgia. 2018;38(12):1805-1816. Doi: https://doi.org/10.1177/0333102417752119

Florencio LL, Ferracni GN, Chaves TC, Palacios-Ceña M, Ordás-Bandera C, Speciali JG, et al. Analysis of Head Posture and Activation of the Cervical Neck Extensors During a Low-Load Task in Women With Chronic Migraine and Healthy Participants. J Manipulative Physiol Ther. 2018;41(9):762-770. Doi: https://doi.org/10.1016/j.jmpt.2018.07.002

Castien RF, van der Wouden JC, De Hertogh W. Pressure pain thresholds over the cranio-cervical region in headache: a systematic review and meta-analysis. J Headache Pain. 2018;19(1):9. Doi: https://doi.org/10.1186/s10194-018-0833-7

Florencio LL, Giantomassi MC, Carvalho GF, Gonçalves MC, Dach F, Fernández-de-Las-Peñas C, et al. Generalized Pressure Pain Hypersensitivity in the Cervical Muscles in Women with Migraine. Pain Med. 2015;16(8):1629-34. Doi: https://doi.org/10.1111/pme.12767

Florencio LL, Chaves TC, Carvalho GF, Gonçalves MC, Casimiro EC, Dach F, et al. Neck pain disability is related to the frequency of migraine attacks: a cross-sectional study. Headache. 2014;54(7):1203-10. Doi: https://doi.org/10.1111/head.12393

Sluka KA, O'Donnell JM, Danielson J, Rasmussen LA. Regular physical activity prevents development of chronic pain and activation of central neurons. J Appl Physiol (1985). 2013;114(6):725-33. Doi: https://doi.org/10.1152/japplphysiol.01317.2012

Sluka KA. How does physical activity modulate pain? Pain. 2017;158(3):369-370. Doi: https://doi.org/10.1097/j.pain.0000000000000792

Bragatto MM, Bevilaqua-Grossi D, Benatto MT, Lodovichi SS, Pinheiro CF, Carvalho GF, et al. Is the presence of neck pain associated with more severe clinical presentation in patients with migraine? A cross-sectional study. Cephalalgia. 2019;39(12):1500-1508. Doi: https://doi.org/10.1177/0333102419854061

Benatto MT, Bevilaqua-Grossi D, Carvalho GF, Bragatto MM, Pinheiro CF, Straceri Lodovichi S, et al. Kinesiophobia Is Associated with Migraine. Pain Med. 2019;20(4):846-851. Doi: https://doi.org/10.1093/pm/pny206

Gil-Martínez A, Navarro-Fernández G, Mangas-Guijarro MÁ, Lara-Lara M, López-López A, Fernández-Carnero J, et al. Comparison Between Chronic Migraine and Temporomandibular Disorders in Pain-Related Disability and Fear-Avoidance Behaviors. Pain Med. 2017;18(11):2214-2223. Doi: https://doi.org/10.1093/pm/pnx127

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Published

2024-09-30

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Original Article

How to Cite

1.
Dantas MIO, Feitosa AS, Ferreira FMQ, Rodrigues IKL, Santos IB dos, Pereira TAB, et al. Patients with chronic migraine present persistent functional disorders in the interictal phase: observational case-control study. Acta Fisiátr. [Internet]. 2024 Sep. 30 [cited 2025 Mar. 9];31(3):146-52. Available from: https://periodicos.usp.br/actafisiatrica/article/view/224224